A human dynein heavy chain mutation impacts cortical progenitor cells causing developmental defects, reduced brain size and altered brain architecture

Delfina M Romero (1) , Donia Zaidi (1) , Carmen Cifuentes-Diaz (1) , Camille Maillard (2) , Gael Grannec (1) , Mohammed Selloum (3) , Marie-Christine Birling (3) , Nadia Bahi-Buisson (2) , Fiona Francis (1)

1 IFM - Inserm U1270 - SU - Institut du Fer à Moulin
2 Equipe Inserm U1163 - Genetics and Development of the Cerebral Cortex
3 IGBMC - Institut de Génétique et de Biologie Moléculaire et Cellulaire

Domaines: Neurosciences [q-bio.NC]; Biologie du développement

Delfina M Romero, Donia Zaidi, Carmen Cifuentes-Diaz, Camille Maillard, Gael Grannec, et al.. A human dynein heavy chain mutation impacts cortical progenitor cells causing developmental defects, reduced brain size and altered brain architecture. Neurobiology of Disease, 2023, 180, pp.106085. ⟨10.1016/j.nbd.2023.106085⟩. ⟨hal-04058455⟩