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How to fix a broken heart: Cardiac disease and the 'multiverse' of stem cell research in Canada

Abstract : This article focuses on Canadian stem cell researchers working on therapeutic appli- cations of autologous stem cells for heart disease. Building on the concept of ‘multiverse’ – coined by William James and then further developed by Ernst Bloch – we are interested in the simultaneity of the certain and uncertain, sometimes contradictory arguments articulated by these scientists. In the first part of the article we illustrate some of the factors that provide certainty for researchers and clinicians. The second part analyzes the ways in which uncertain elements become integrated into a discourse of certainty. What we would like to show, using the concept of multiverse, is that a rela- tively new bio-technology such as stem cell treatments generally relies on both certain and uncertain reasoning. However, uncertainty has to give way to a platform of partial certainty, if crucial action is to be taken on issues as diverse as treatments and grant applications. The principle mechanisms we found that can make this kind of transformation possible target future developments (what we call ‘if only arguments’), including past encouraging results in need of further research.
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Annette Leibing, Virginie Tournay, Rachel Aisengart Menezes, Rafaela Zorzanelli. How to fix a broken heart: Cardiac disease and the 'multiverse' of stem cell research in Canada. BioSocieties, Palgrave Macmillan, 2016, 11 (4), pp.435-457. ⟨10.1057/biosoc.2016.5⟩. ⟨hal-01630606⟩

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